Summer 2025 - Quantitative systems Pharmacology & Physiologically Based Pharmacokinetics Internship
Company: Disability Solutions
Location: Princeton
Posted on: October 19, 2024
Job Description:
Working with UsChallenging. Meaningful. Life-changing. Those
aren't words that are usually associated with a job. But working at
Bristol Myers Squibb is anything but usual. Here, uniquely
interesting work happens every day, in every department. From
optimizing a production line to the latest breakthroughs in cell
therapy, this is work that transforms the lives of patients, and
the careers of those who do it. You'll get the chance to grow and
thrive through opportunities uncommon in scale and scope, alongside
high-achieving teams rich in diversity. Take your career farther
than you thought possible.Bristol Myers Squibb recognizes the
importance of balance and flexibility in our work environment. We
offer a wide variety of competitive benefits, services and programs
that provide our employees with the resources to pursue their
goals, both at work and in their personal lives. Read more:
.Position SummaryWe are seeking passionate and skilled college and
graduate students who look for opportunities to learn, to grow, and
work alongside talented career QSP&PBPK scientists. The Intern
will work in BMS Clinical Pharmacology, Pharmacometrics, and
Bioanalysis (CPPB) Department with specific focus on mechanistic
modeling projects, under the guidance of a scientist experienced in
the development and improvement of models. Depending on the
projects prioritized by the advisors and the department, the intern
may have different specific goals. Potential projects include but
are not limited to the assessment and development of methods for
efficient characterization and prediction of small molecule
absorption, distribution, metabolism, excretion, and drug-drug
interactions; development of new models for other modalities; or
developing and parameterizing mini-models for other pathways and
processes of interest as relevant for discovery, toxicology, and
clinical efforts and incorporating them into a platform. The
project can involve testing the functionality of the models in the
context of different therapies and helping with data analysis to
advance research and development programs.As part of the Bristol
Myers Squibb Virtual Intern Program the successful candidate will
have cross-functional networking opportunities for personal and
professional development.Potential Responsibilities
- Develop and parametrize mechanistic models using systems of
ordinary differential equations
- Calibrate parametrized mini-models using in-house data or data
available in the public domain
- Identify and determine physiological range of the most
sensitive parameters
- Incorporate pathway knowledge into platforms and test
functionality with respect to existing therapies
- Assist in the analysis of discovery, toxicology, and clinical
data
- Participate in the BMS Virtual Intern Program
activitiesQualifications & Experience
- Student in mathematics, engineering (chemical, biomedical,
others), physics, or pharmaceutical disciplines including drug
metabolism and pharmacokinetics with strong mathematical
background
- Solid knowledge of modeling using ordinary differential
equations and numerical solvers
- Knowledge of how to perform parameter estimation and
sensitivity analysis
- Experience with MATLAB/SimBiology environment is beneficial If
you come across a role that intrigues you but doesn't perfectly
line up with your resume, we encourage you to apply anyway. You
could be one step away from work that will transform your life and
career. Uniquely Interesting Work, Life-changing CareersWith a
single vision as inspiring as Transforming patients' lives through
science--- , every BMS employee plays an integral role in work that
goes far beyond ordinary. Each of us is empowered to apply our
individual talents and unique perspectives in an inclusive culture,
promoting diversity in clinical trials, while our shared values of
passion, innovation, urgency, accountability, inclusion and
integrity bring out the highest potential of each of our
colleagues.On-site Protocol BMS has a diverse occupancy structure
that determines where an employee is required to conduct their
work. This structure includes site-essential, site-by-design,
field-based and remote-by-design jobs. The occupancy type that you
are assigned is determined by the nature and responsibilities of
your role: Site-essential roles require 100% of shifts onsite at
your assigned facility. Site-by-design roles may be eligible for a
hybrid work model with at least 50% onsite at your assigned
facility. For these roles, onsite presence is considered an
essential job function and is critical to collaboration,
innovation, productivity, and a positive Company culture. For
field-based and remote-by-design roles the ability to physically
travel to visit customers, patients or business partners and to
attend meetings on behalf of BMS as directed is an essential job
function. BMS is dedicated to ensuring that people with
disabilities can excel through a transparent recruitment process,
reasonable workplace accommodations/adjustments and ongoing support
in their roles. Applicants can request a reasonable workplace
accommodation/adjustment prior to accepting a job offer. If you
require reasonable accommodations/adjustments in completing this
application, or in any part of the recruitment process, direct your
inquiries to . Visit to access our complete Equal Employment
Opportunity statement. BMS cares about your well-being and the
well-being of our staff, customers, patients, and communities. As a
result, the Company strongly recommends that all employees be fully
vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest
and conviction records, pursuant to applicable laws in your area.If
you live in or expect to work from Los Angeles County if hired for
this position, please visit this page for important additional
information: Any data processed in connection with role
applications will be treated in accordance with applicable data
privacy policies and regulations.
Keywords: Disability Solutions, Norwalk , Summer 2025 - Quantitative systems Pharmacology & Physiologically Based Pharmacokinetics Internship, Other , Princeton, Connecticut
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